New TV this week: 7 shows premiering on Netflix, Hulu and more (Sept. 23-29)

Melissa McBride and Norman Reedus in The Walking Dead: Daryl Dixon
(Image credit: AMC)

Do you hear that sound? It's all the new TV shows dropping faster than leaves this week on Netflix, Hulu and other streaming services, as well as broadcast and cable channels.

The new TV lineup is stacked with stars. Kristen Bell and Adam Brody pair up in the rom-com "Nobody Wants This," Joshua Jackson brings his charm to the open seas in "Doctor Odyssey" and Travis Kelce tries his hand at acting in "Grotesquerie." Plus, several returning favorites are back with seasons, including "Grey's Anatomy" and "The Walking Dead: Daryl Dixon." Here's our guide on the top new TV shows to check out this week.

‘Brilliant Minds’ (NBC)

Zachary Quinto is Eccentric Dr. Wolf in NBC’s New Medical Drama Brilliant Minds | Official Trailer - YouTube Zachary Quinto is Eccentric Dr. Wolf in NBC’s New Medical Drama Brilliant Minds | Official Trailer - YouTube
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The “eccentric but brilliant doctor” trope has been successful in shows ranging from “House” to “The Good Doctor.” The latest in line is “Brilliant Minds,” which centers on Dr. Oliver Wolf (Zachary Quinto), a neurologist who suffers from a rare condition that gives him a unique perspective on care. When his unconventional methods get him fired, he takes a job at Bronx General to lead a team of bright young interns tackling some of the world's most puzzling psychological cases. 

Premieres Monday, Sept. 23 at 10 p.m. ET on NBC (via Sling or Fubo)
Episodes stream next day on
Peacock

‘Grotesquerie’ (FX)

Grotesquerie | Official Trailer | Niecy Nash-Betts, Courtney B. Vance, Lesley Manville, Travis Kelce - YouTube Grotesquerie | Official Trailer | Niecy Nash-Betts, Courtney B. Vance, Lesley Manville, Travis Kelce - YouTube
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The parade of Ryan Murphy shows will seemingly never end, with this horror thriller and a procedural medical drama on deck (in the latter case, literally — see below). “Grotesquerie” may best be known as the acting debut of Travis Kelce, aka Mr. Taylor Swift. After a series of heinous crimes unsettles a small community, Detective Lois Tryon (Niecy Nash-Betts) feels the cases are eerily personal, as if someone — or something) is taunting her. With no leads and her home life in disarray, Lois seeks the help of Sister Megan (Micaela Diamond), a nun and journalist. Together, they begin to string together clues, but soon find themselves ensnared in a sinister web. 

Premieres Wednesday, Sept. 25 at 10 p.m. ET on FX (via Sling or Fubo)
Episodes stream next day on
Hulu

‘Nobody Wants This’ (Netflix)

Nobody Wants This | Official Trailer | Netflix - YouTube Nobody Wants This | Official Trailer | Netflix - YouTube
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Veronica Mars and Seth Cohen? Sign me up! The former stars of mid-aughts teen shows pair up for this charming rom-com series about an agnostic podcast host and an unconventional rabbi. As unlikely of a couple as they make, Joanne and Noah feel an undeniable zing between them when they meet at a party. Still, their differing views, the usual modern obstacles to love and their well-meaning but difficult families won’t make their romantic journey easy.

Premieres Thursday, Sept. 26 at 3 a.m. ET on Netflix

‘Doctor Odyssey’ (ABC)

OFFICIAL TRAILER - Doctor Odyssey - YouTube OFFICIAL TRAILER - Doctor Odyssey - YouTube
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Mega-producer Ryan Murphy expands his televisual universe with this procedural medical drama starring Joshua Jackson as the new on-board doctor of a luxury cruise ship where the staff works hard and plays harder. Under the eye of Captain Robert Massey (Don Johnson), Max and his small but mighty team — including nurses Avery Morgan (Phillipa Soo) and Tristan Silva (Sean Teale) navigate unique medical crises on the high seas miles from shore. 

Premieres Thursday, Sept. 26 at 9 p.m. ET on ABC (via Sling or Fubo)
Episodes stream next day on
Hulu

‘Grey’s Anatomy’ season 21 (ABC)

Grey's Anatomy Season 21 OFFICIAL TRAILER - Premieres THURS SEPT 26 on ABC - Stream on Hulu - YouTube Grey's Anatomy Season 21 OFFICIAL TRAILER - Premieres THURS SEPT 26 on ABC - Stream on Hulu - YouTube
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Two new medical dramas are debuting this week, but the grand dame of them all is still going strong. Season 21 (twenty-one!) will see star Ellen Pompeo return as Meredith Grey in more episodes than in the previous two seasons. Meredith is squaring off against Catherine Fox (Debbie Allen) over her Alzheimer’s research. Plus, she goes to bat for Amelia (Caterina Scorsone), Owen (Kevin McKidd) and Teddy (Kim Raver), who were all fired for helping her. Meanwhile, Jo (Camilla Luddington) grapples with her pregnancy, which she still hasn’t revealed to Link (Chris Carmack). 

Premieres Thursday, Sept. 26 at 10 p.m. ET on ABC (via Sling or Fubo)
Episodes stream next day on
Hulu

‘Saturday Night Live’ season 50 (NBC)

SNL Is Returning for Season 50! - YouTube SNL Is Returning for Season 50! - YouTube
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The iconic sketch comedy series returns for a historic 50th season, just ahead of the biopic “Saturday Night” about its 1975 premiere. Season 50 will kick off with host Jean Smart, who just won an Emmy for “Hacks,” and musical guest Jelly Roll. Three new featured players are joining the cast: Ashley Padilla of The Groundlings, stand-up comic Emil Wakim, and TikToker Jane Wickline. With the election fast approaching, expect plenty of political sketches featuring alum Maya Rudolph as Vice President Kamala Harris. 

Premieres Saturday, Sept. 28 at 11:30 p.m. ET on NBC (via Sling or Fubo)
Episodes stream next day on
Peacock

‘The Walking Dead: Daryl Dixon’ season 2 (AMC)

The Walking Dead: Daryl Dixon - The Book Of Carol | Official Trailer | Feat. Norman Reedus - YouTube The Walking Dead: Daryl Dixon - The Book Of Carol | Official Trailer | Feat. Norman Reedus - YouTube
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Two of the best and most memorable characters from “The Walking Dead” anchor this spinoff, which picks up where it left off. Season 2 finds Daryl Dixon (Norman Reedus) and Carol Peletier (Melissa McBride) confronting old demons while she fights to find her friend and he struggles with his decision to stay in France. They will get caught up in the coming battle between Genet's (Anne Charrier) movement Pouvoir and the Union of Hope for the future of the country.

Premieres Sunday, Sept. 29 at 9 p.m. ET on AMC (via Sling or Fubo)

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Kelly Woo
Streaming Editor

Kelly is the streaming channel editor for Tom’s Guide, so basically, she watches TV for a living. Previously, she was a freelance entertainment writer for Yahoo, Vulture, TV Guide and other outlets. When she’s not watching TV and movies for work, she’s watching them for fun, seeing live music, writing songs, knitting and gardening.