System design thoughts...

Care should be taken when selecting a motherboard not only from a chipset point of view but also where the manufacturer has located the CPU socket, DIMM sockets, IDE and FDD sockets.
Some manufacturers locate the IDE socket in the bottom right corner which mandates the use of a long IDE cable to reach the drive/s especially when the drives are mounted high in a full-tower case.
FDD sockets are usually located near the upper right corner which is prime real-estate.
motherboards like the ASUS M2N-32 mount the DIMM sockets horizontally above the CPU socket while some Gigabyte models mount the DIMM sockets vertically beside the CPU socket.
Each design has it's pros and cons and should be considered.

Choosing a case is another area that has many considerations to be factored in such as:
how many 5.25" devices are you planning to install ?
where do you want the PSU, top or bottom ?
how quiet do you want the system to be ?
which CPU cooler have you chosen ?
where do you want the HDD's ?
do you want clear side-panels ?
does it have sufficient airflow for your needs ?
These are all important factors to consider.

What a great idea; when i designed this system i selected
a Thermaltake Armor full-tower case: http://www.newegg.com/Product/Prod [...] 6811133021
Eleven 5.25" drive bays enabled me to use a pair of 120mm
fans in the front using up 6 of the available bays, this left
4 bays open for the DVD/ROM; DVD Read/Write;
Card reader/USB 2.0/firewire; and the fan controller;
the FDD was integrated with the power/reset switch panel.

The stock case has 2 fans on the back wall; a 120mm and
a 90mm unit, I removed the 90mm fan on the back wall and
the 90mm fan on the ceiling because they were real noisy
and created too much negative airflow, Rear case fans
now include a 120mm and the PSU fan which is also 120mm.
The case vent on top and the 90mm case vent on the
back panel were sealed up to promote desired airflow thru
the case as well, in thru the lower front
and out thru the upper rear.

Choice of platform is AM2 socket so the ASUS M2N32-SLI WiFi
was a no-brainer with it's 590 chipset and great features:
http://www.newegg.com/Product/Prod [...] 6813131011

My choice for Seagate Barracudas: http://www.newegg.com/Product/Prod [...] 6822148140
was simple; they're quiet, fast and reliable;
I setup a pair of them up in RAID(1) for complete
redundancy then mounted them low in the front
of the case inside passive coolers: http://www.newegg.com/Product/Prod [...] 6835185040
Each HDD enclosure is centered directly behind each
of the 2 front bay fans where they get plenty of air.
Presently I'm using a mixture of Thermaltake and Logisys LED
case fans which are being replaced by Scythe Minebea units: http://www.newegg.com/Product/Prod [...] 6835185028
The Scythe units will provide optimal airflow and minimal noise;
the LED fans are going in the spare parts box in favor
of discreet LED case lighting using Blue CCFL's:
http://www.newegg.com/Product/Prod [...] 6811994001
and laser LED's:
http://www.newegg.com/Product/Prod [...] 6800884026
Temperatures are handled by Thermalright;
Ultra-120 Extreme
http://www.newegg.com/Product/Prod [...] 6835109140
for the Athlon64 X2 6000+ http://www.newegg.com/Product/Prod [...] 6819103773
and the HR-03+
http://www.newegg.com/Product/Prod [...] 6835109136
for the 8800GTS 320MB video card
http://www.newegg.com/Product/Prod [...] 6835109136
Add 1 more 120mm fan for the Ultra-120 and a
92mm for the HR-03+.
The large heatsinks on the CPU and GPU are very
efficient and require minimal airflow to achieve
superior cooling; CPU temps are 38C @ idle and
45C @ 50%load.
GPU temps dropped from 65C to 52C under load.
I make it a point to route all the power cables
carefully and tuck them up against the motherboard
tray too avoid disruption of airflow thru the case.