No, because esata is only for disk and usb 3.0 is for other stuff as well. Therefore, it is possible to have esata on usb 3.0 but not the other way around. Your best choice is to use your expresscard slot (if you have one) and get a usb 3.0 card for it. It should not bottleneck your single hdd but the expresscard bandwidth will bottleneck the newest fast ssd.